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Cost utility of sequential adjuvant trastuzumab for HER2/Neu-positive breast cancer

Shelby D Reed1, Kevin A Schulman

  • 1Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA. shelby.reed@duke.edu

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
|May 29, 2009
PubMed
Abstract

No abstract available in PubMed .

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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