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Updated: Jun 22, 2026
Analyzing the Functions of Mast Cells In Vivo Using 'Mast Cell Knock-in' Mice
Published on: May 27, 2015
CD4 expression by mast cells in mastocytosis: a case report
E J Soilleux1, J Bowling, K Hollowood
1Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK. elizabeth.soilleux@orh.nhs.uk
Abstract:
A 59-year-old man presented with a five-year history of an asymptomatic widespread truncal rash. Cutaneous biopsies showed mastocytosis, which was shown to be CD4-positive immunohistochemically. This potential diagnostic pitfall in the discrimination of mastocytosis from a variety of other haematopoietic neoplasms, particularly mycosis fungoides, is discussed.
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