Related Experiment Video
Updated: Jun 22, 2026
10:37
Development of Recombinant Proteins to Treat Chronic Pain
Published on: April 11, 2018
[Intrathecal drugs for chronic pain control.]
Anita Perpétua Carvalho Rocha1, Lino Lemonica, Guilherme Antônio Moreira de Barros
1Departamento de Anestesiologia, Serviço de Terapia Antálgica e Cuidados Paliativos, FMB, UNESP.
Revista Brasileira De Anestesiologia
|May 29, 2009
Summary
Intrathecal drug administration offers a safe and effective approach for chronic pain management. This review analyzes established and novel agents, guiding clinical practice and future research.
Area of Science:
- Pharmacology
- Pain Management
- Neurology
Context:
- Chronic pain presents a significant challenge in modern medicine.
- Intrathecal drug administration is a viable and safe route for pain control, necessitating further investigation.
- This review focuses on established and emerging therapeutic options for daily clinical practice.
Purpose:
- To review available and novel drugs for intrathecal administration in chronic pain management.
- To analyze the desirable and undesirable effects of various drug classes used neuraxially.
- To provide insights for healthcare professionals managing chronic pain.
Summary:
- The study reviews neuraxial drugs including opioids, local anesthetics, alpha2-agonists, and others for their analgesic properties.
- Analysis includes the benefits and drawbacks of each drug class for intrathecal use.
- Advances in intrathecal pain management are discussed, highlighting potential therapeutic additions and exclusions.
Impact:
- Several advances have been made in controlling chronic pain via intrathecal drug administration.
- Some reviewed drugs will likely be incorporated into therapeutic regimens, while others may be discontinued.
- Further clinical and experimental studies are essential for integrating new knowledge safely into chronic pain management practices.
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