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[Continuous epidural anesthesia with 0.2% ropivacaine associated to general anesthesia for upper abdominal surgery in
Jyrson Guilherme Klamt1, Luis Vicente Garcia, Renato Mestriner Stocche
1Disciplina de Anestesiologia, Dept masculine de Biomecânica, Medicina e Reabilitação do Aparelho Locomotor, Faculdade de Medicina de Ribeirao Preto, USP.
Insights
Adding sufentanil to propofol infusion during pediatric upper abdominal surgery under epidural anesthesia reduced propofol requirements and sedation duration. Both anesthetic techniques provided effective and safe recovery for children.
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Pharmacology
Context:
- Pediatric upper abdominal surgeries require effective anesthesia and analgesia.
- Epidural anesthesia combined with general anesthesia is a common approach.
- Optimizing anesthetic agents like propofol and sufentanil is crucial for patient recovery.
Purpose:
- To evaluate the impact of propofol infusion rate and postanesthetic recovery in pediatric patients undergoing upper abdominal surgery.
- To compare general anesthesia with propofol versus propofol plus sufentanil, combined with epidural anesthesia (0.2% ropivacaine).
Summary:
- This study involved 26 pediatric patients (ASA I-III, 0-4 years) receiving thoracic epidural anesthesia with ropivacaine and general anesthesia with either propofol or propofol plus sufentanil.
- The Sufentanil group required a slower propofol infusion rate. While the Propofol group had faster extubation and transfer to the post-anesthetic recovery unit (PACU), they experienced longer sedation.
- Recovery scores were comparable, with all patients ready for ward transfer within three hours of PACU admission. Transient hypotension occurred in two patients in the Sufentanil group.
Impact:
- Continuous thoracic epidural anesthesia with ropivacaine and propofol infusion is safe and effective for pediatric upper abdominal surgeries.
- The addition of sufentanil to propofol infusion decreases propofol requirements and sedation duration.
- Findings guide anesthetic choices to improve pediatric surgical recovery and safety.
Background And Objectives:
Several anesthetic techniques have been proposed for different pediatric surgeries to promote postoperative analgesia, among other advantages. This study aimed at evaluating propofol infusion rate and postanesthetic recovery of children submitted to upper abdominal surgeries under epidural anesthesia with 0.2% ropivacaine associated to general anesthesia with propofol or propofol plus sufentanil.
Methods:
Participated in this study 26 children physical status ASA I, II and III, aged 0 to 4 years, were scheduled to upper abdominal surgeries under thoracic epidural anesthesia (T7-T8) with 0.2% ropivacaine (1.5 ml.kg-1). They were randomly distributed in two groups: Propofol (propofol infusion) and Sufentanil (propofol infusion plus 1 microg.kg-1 sufentanil). Propofol infusion rates were 20 and 10 mg.kg-1.h-1 for the Propofol and Sufentanil groups, respectively, adjusted to maintain blood pressure in approximately 20% of baseline values and withdrawn 10 to 15 minutes before estimated surgery completion. Postanesthetic recovery was evaluated by a modified Aldrete-Kroulik scale and sedation was evaluated by a 5 grade score.
Results:
Techical difficulties excluded two children of each group. Infusion rate was significantly slower in the Sufentanil group as compared to the Propofol group during 100 minutes after beginning of surgery. Time for extubation and referral to post-anesthetic recovery unit (PACU) was significantly shorter for the Propofol group, however sedation intensity and duration were longer in this group as compared to Sufentanil group. Recovery scores were similar for both groups. Three hours after PACU admission all patients were meeting criteria to be transferred to the ward. Transient arterial hypotension was observed in 2 Sufentanil group patients.
Conclusions:
Continuous thoracic epidural anesthesia with 0.2% ropivacaine (1.5 mg.kg-1) associated to propofol infusion provides effective and safe anesthesia for upper pediatric abdominal surgeries. Propofol infusion rate and sedation duration were decreased with the association of sufentanil.
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