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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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From pollinosis to digestive allergy.

J Bartra1, J Sastre, A del Cuvillo

  • 1Unitat d'Allèrgia, Servei de Pneumologia i Allèrgia Respiratòria, Hospital Clinic (ICT), Barcelona, Spain. jbartra@clinic.ub.es

Journal of Investigational Allergology & Clinical Immunology
|May 30, 2009
PubMed
Summary

Pollen allergy (pollinosis) can cause respiratory issues and lead to plant food allergies through cross-reactivity. It may also directly cause digestive inflammation and eosinophilic esophagitis.

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Area of Science:

  • Immunology
  • Allergology
  • Gastroenterology

Background:

  • Pollinosis involves respiratory symptoms from pollen inhalation in sensitized individuals.
  • Pollen allergy is linked to plant food allergies and digestive tract inflammation.
  • Cross-reactivity between inhaled pollen allergens and food allergens is a key mechanism.

Purpose of the Study:

  • To explore the connection between pollinosis and plant food allergies.
  • To investigate the role of pollen in digestive allergic conditions.
  • To understand the mechanisms linking airway and digestive tract allergic responses.

Main Methods:

  • Review of existing literature on pollinosis and allergic cross-reactivity.
  • Analysis of the impact of geographical and dietary factors on pollen-food allergy patterns.
  • Examination of the immunological pathways involved in pollinosis-related digestive inflammation.

Main Results:

  • Pollinosis can precede or coincide with plant food allergies due to shared allergens.
  • Pollen exposure can directly trigger digestive inflammation, including eosinophilic esophagitis.
  • The prevalence and severity of plant food allergies are influenced by local pollination and dietary habits.

Conclusions:

  • Pollinosis is a significant factor in the development and manifestation of plant food allergies.
  • Mechanisms beyond simple cross-reactivity link pollinosis to digestive allergic diseases.
  • Systemic allergic responses in pollinosis can impact the digestive tract, highlighting the airway-gut connection.