Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Upper Respiratory Drugs: First and Second-Generation Antihistamines01:15

Upper Respiratory Drugs: First and Second-Generation Antihistamines

Antihistamines are a class of drugs widely used to alleviate the symptoms of allergies, such as sneezing, itching, and nasal congestion. They work by inhibiting the actions of histamine, which is released by immune cells in response to allergenic substances or tissue injuries.
Histamine binds to specific receptor sites, known as H1 receptors, on tissue cells, triggering inflammation and swelling. Antihistamines combat these effects by competing with histamine for these receptor sites. By...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Lamella Ostium Extent Mucosa (LOEM) system: a new classification for endoscopic sinus surgery.

Rhinology·2024
Same author

Baseline Clinical Characteristics and Phenoendotypes of Patients With Severe Asthma in Alergodata: The Spanish Allergy Society Registry.

Journal of investigational allergology & clinical immunology·2024
Same author

ALERGODATA: Sentinel Registry of Health Outcomes in Allergic Patients Treated With Biological Therapies at Specialized Allergology Clinics in Spain.

Journal of investigational allergology & clinical immunology·2023
Same author

Spanish Consensus on the Management of Chronic Rhinosinusitis With Nasal Polyps (POLIposis NAsal/POLINA 2.0).

Journal of investigational allergology & clinical immunology·2023
Same author

Transcriptional analysis of nasal polyps fibroblasts reveals a new source of pro-inflammatory signaling in CRSwNP.

Rhinology·2023
Same author

Severity and duration of allergic conjunctivitis: are they associated with severity and duration of allergic rhinitis and asthma?

European annals of allergy and clinical immunology·2021
Same journal

Safety, Adherence, and Effectiveness of an Increased Dose of Pollinex Quattro Grass and/or Olive in Real-World Practice.

Journal of investigational allergology & clinical immunology·2026
Same journal

Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Moderate-to-Severe Asthma, Type 2 Inflammation, and Nocturnal Awakenings: The MORPHEO Randomized Controlled Trial.

Journal of investigational allergology & clinical immunology·2026
Same journal

Severe Rituximab-Induced Cytokine Release Syndrome After Desensitization Successfully Treated With Tocilizumab: A Case Report.

Journal of investigational allergology & clinical immunology·2026
Same journal

Dysregulation of Mast Cell Prostaglandin in Food Anaphylaxis.

Journal of investigational allergology & clinical immunology·2026
Same journal

Extract-Negative Cofactor-Dependent Shrimp Anaphylaxis Caused by IgE Reactivity to Insoluble Muscle Proteins.

Journal of investigational allergology & clinical immunology·2026
Same journal

Antibiotic Allergy Labels in Hospitalized Patients: Results of a Multicenter Cross-Sectional Study.

Journal of investigational allergology & clinical immunology·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Allergic rhinitis and school performance.

I Jáuregui1, J Mullol, I Dávila

  • 1Servicio de Alergología, Hospital de Basurto, Bilbao, Spain. ignacio.jaureguipresa@osakidetza.net

Journal of Investigational Allergology & Clinical Immunology
|May 30, 2009
PubMed
Summary
This summary is machine-generated.

Allergic rhinitis significantly impacts children's school performance. Effective treatments like second-generation antihistamines and intranasal corticosteroids can improve academic outcomes by managing symptoms and sleep disturbances.

More Related Videos

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Related Experiment Videos

Last Updated: Jun 22, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Area of Science:

  • Pediatric Allergy and Immunology
  • Childhood Health Outcomes

Background:

  • Allergic rhinitis is a prevalent chronic condition in children.
  • Symptoms include sleep disturbances, daytime sleepiness, and cognitive impairment, negatively affecting school performance.
  • First-generation antihistamines carry risks of central and anticholinergic effects, potentially worsening the condition.

Purpose of the Study:

  • To evaluate the impact of allergic rhinitis on pediatric school performance.
  • To identify effective treatment strategies for improving academic outcomes in children with allergic rhinitis.

Main Methods:

  • Review of current literature on allergic rhinitis management in children.
  • Analysis of the effects of various pharmacologic agents on symptom control and cognitive function.
  • Assessment of the relationship between allergic rhinitis treatment and school performance indicators.

Main Results:

  • Second-generation antihistamines are recommended for treating allergic rhinitis in children.
  • Intranasal corticosteroids may improve school performance by alleviating nasal congestion and sleep issues.
  • Vasoconstrictors are contraindicated in pediatric patients due to safety concerns.

Conclusions:

  • Appropriate management of allergic rhinitis is crucial for enhancing children's school performance.
  • Second-generation antihistamines and intranasal corticosteroids are key therapeutic options.
  • Further research is needed on the impact of other treatments like immunotherapy on academic outcomes.