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Updated: Jun 22, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

[Recurrent upper respiratory tract infections in children and allergy. A cross-sectional study of 100 cases]

Chiraz Mbarek1, Amel Akrout, Khaled Khamassi

  • 1Service d'ORL et de chirurgie cervico-faciale, Hôpital Habib Thameur, Tunis, Tunisie.

La Tunisie Medicale
|May 30, 2009
PubMed

Insights

Allergy is a significant risk factor for recurrent upper respiratory tract (URT) infections in children. Managing allergy can help prevent and treat conditions like rhinopharyngitis, rhinosinusitis, and acute otitis media.

Area of Science:

  • Pediatric Health
  • Immunology
  • Otolaryngology

Background:

  • Recurrent upper respiratory tract (URT) infections are prevalent in children.
  • Identifying risk factors aids in managing URT infections.
  • The study investigates the potential link between allergy and URT infections.

Purpose of the Study:

  • To determine the role of allergy as a risk factor for recurrent URT infections in children.
  • To assess the association between allergy and specific URT pathologies.

Main Methods:

  • A cross-sectional study was conducted on approximately 100 children with recurrent URT infections.
  • Allergy prevalence was evaluated to establish correlations with URT pathologies.
  • Results were compared against a reference group of 164 children.

Main Results:

  • A statistically significant association was found between allergy and recurrent URT infections (p=0.01).
  • Specific links were identified between allergy and rhinopharyngitis (p=0.02), rhinosinusitis (p=0.001), and acute otitis media (p=0.01).

Conclusions:

  • Allergy is confirmed as a risk factor for recurrent URT infections in pediatric populations.
  • Allergy is particularly linked to rhinopharyngitis, rhinosinusitis, and acute otitis media.
  • Effective allergy management may improve treatment and prevention of these common childhood infections.
Abstract

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