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Characterization of a specific interaction between ADAM23 and cellular prion protein

Michele D M Costa1, Katia S Paludo, Giseli Klassen

  • 1Department of Basic Pathology, Universidade Federal do Paraná, Centro Politécnico, 81531-990 Curitiba, PR, Brazil.

Neuroscience Letters
|May 30, 2009
PubMed
Summary

Cellular prion protein (PrP(C)) interacts with ADAM23, a protein crucial for nervous system development. This discovery reveals PrP(C) as a new binding partner for ADAM23 in the central nervous system.

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