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Related Experiment Video

Updated: Jun 22, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Left ventricular apical thinning as normal anatomy.

Kevin M Johnson¹, Hilary E Johnson, David A Dowe

¹Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA. kevin.johnson@yale.edu

Journal of Computer Assisted Tomography

|May 30, 2009

Summary

This summary is machine-generated.

Apical thinning of the left ventricular myocardium is a normal feature in healthy individuals and those with left ventricular hypertrophy. This finding was consistently observed using coronary computed tomographic arteriography (CCTA).

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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

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Last Updated: Jun 22, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

Area of Science:

Cardiovascular Anatomy
Cardiac Imaging

Background:

Apical thinning of the left ventricular myocardium is a recognized anatomical feature.
This normal finding is often absent in anatomical atlases.

Purpose of the Study:

To investigate the presence of left ventricular apical thinning in healthy individuals and patients with left ventricular hypertrophy.
To utilize coronary computed tomographic arteriography (CCTA) for this investigation.

Main Methods:

Coronary computed tomographic arteriography (CCTA) was performed on 64 healthy patients and 8 patients with left ventricular hypertrophy.
Quantitative measurements of apical thinning were recorded.

Main Results:

All 64 healthy patients exhibited a focus of myocardial thinning at the left ventricular apex (mean thickness 1.2 mm).
The 8 patients with left ventricular hypertrophy also presented with apical thinning.
Functional analysis in a subset of 12 patients showed no thickening or movement of the thinned apex during the cardiac cycle.

Conclusions:

A zone of significant thinning at the left ventricular apex is a normal anatomical characteristic.
This finding is present in both healthy individuals and those with left ventricular hypertrophy.