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Prevalence of vertebral pars defects (spondylolysis) in a population with osteogenesis imperfecta
Wiebe C Verra1, Hans J Pruijs, Erik J Beek
1Department of Orthopedics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Study Design:
We performed a retrospective study of spinal roentgenograms of a large cohort of patients suffering from osteogenesis imperfecta.
Objective:
To determine the prevalence of vertebral pars defects (spondylolysis) in patients with osteogenesis imperfecta.
Summary Of Background Data:
Patients suffering from osteogenesis imperfecta are known to be prone to pathologic fractures. Pathologic fractures due to microtraumas, repetitive activities, and posture acting together on a congenitally weakened pars interarticularis may lead to vertebral pars defects. The prevalence of vertebral pars defects in patients with osteogenesis imperfecta has never been studied before to our knowledge.
Methods:
We performed a retrospective study of posterior-anterior and lateral, standing, roentgenograms of the spine of patients with osteogenesis imperfecta for the occurrence of vertebral pars interarticularis defects.
Results:
The patients (5.3%) in our series showed vertebral pars defects, this is not significantly different from the prevalence of vertebral pars defects in the general population.
Conclusion:
5.3% of the patients with osteogenesis imperfecta showed vertebral pars defects, this does not differ significantly from the occurrence in the general population.
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