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Emergence agitation in children after propofol versus halothane anesthesia

Antigona Hasani1, Serpil Ozgen2, Nehat Baftiu3

  • 1Department of Anesthesiology and Intensive Care, University Clinical Center of Kosova, Pristina, Kosovo.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|May 30, 2009
PubMed

Insights

Propofol anesthesia in children leads to more emergence agitation compared to halothane. Halothane anesthesia resulted in less agitation, though recovery was slower.

Area of Science:

  • Pediatric Anesthesiology
  • Pharmacology
  • Surgical Care

Background:

  • Emergence agitation is common in children post-anesthesia.
  • Halothane and propofol are anesthetic agents with differing effects on emergence agitation.
  • The Pediatric Anesthesia Emergence Delirium (PAED) scale is used to assess agitation.

Purpose of the Study:

  • To compare the incidence of emergence agitation in pediatric patients receiving propofol versus halothane anesthesia.
  • To evaluate the effectiveness of different anesthetic agents in minimizing emergence agitation.
  • To analyze factors influencing emergence agitation in pediatric surgical patients.

Main Methods:

  • 83 children aged 1-6 years were divided into two groups: propofol (n=41) and halothane (n=42).
  • Anesthesia was maintained with propofol (9.0 mg/kg/h) or halothane (1.5-2%) with fentanyl.
  • Pediatric Anesthesia Emergence Delirium (PAED) scale, recovery time, anxiety, and pain were assessed.

Main Results:

  • Propofol group showed a significantly higher incidence of emergence agitation (29.3%) compared to halothane group (9.5%).
  • The PAED scale scores were higher in the propofol group (8) than in the halothane group (4).
  • Mean recovery time was significantly shorter with propofol (16.1 min) than halothane (20.5 min).

Conclusions:

  • Propofol maintenance anesthesia is associated with a higher incidence of emergence agitation in children than halothane.
  • Halothane anesthesia may be preferable for minimizing emergence agitation in pediatric patients.
  • While propofol offers faster recovery, it increases the risk of emergence agitation.
Abstract

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