Anaerobic-to-aerobic power ratio in children with juvenile idiopathic arthritis

Marco van Brussel1, Lieke van Doren, Brian W Timmons

  • 1Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

Insights

Children with juvenile idiopathic arthritis (JIA) show similar anaerobic-to-aerobic power ratios compared to healthy peers. Exercise interventions combining anaerobic and aerobic training may benefit children with JIA.

Area of Science:

  • Pediatric Rheumatology
  • Exercise Physiology
  • Sports Medicine

Background:

  • Juvenile idiopathic arthritis (JIA) can impact physical function.
  • Understanding energy system development in JIA is crucial for rehabilitation.

Purpose of the Study:

  • To compare the anaerobic-to-aerobic power ratio in children with JIA versus healthy controls.
  • To investigate factors influencing this ratio in pediatric populations.

Main Methods:

  • Cross-sectional study involving 62 children with JIA and 50 healthy children.
  • Anaerobic power assessed via Wingate Anaerobic Exercise Test.
  • Aerobic power measured using cardiopulmonary exercise testing.

Main Results:

  • No statistically significant differences in mean or peak anaerobic-to-aerobic power ratios were found between children with JIA and healthy peers.
  • These findings remained consistent after adjusting for age, height, and body mass.
  • No significant differences were observed across JIA onset types, sexes, or between JIA patients and controls over time.

Conclusions:

  • The development of the anaerobic-to-aerobic power ratio is comparable in children with JIA and healthy children.
  • Interval training for anaerobic capacity and aerobic exercise training are recommended for JIA management.
Abstract

Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.