Related Experiment Video
Updated: Jun 22, 2026

Evaluation of Changes in Hydration and Body Cell Mass with Bioelectrical Impedance Analysis after Exercise Program for Rheumatoid Arthritis Patients
Published on: July 14, 2023
Anaerobic-to-aerobic power ratio in children with juvenile idiopathic arthritis
Marco van Brussel1, Lieke van Doren, Brian W Timmons
1Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Insights
Children with juvenile idiopathic arthritis (JIA) show similar anaerobic-to-aerobic power ratios compared to healthy peers. Exercise interventions combining anaerobic and aerobic training may benefit children with JIA.
Area of Science:
- Pediatric Rheumatology
- Exercise Physiology
- Sports Medicine
Background:
- Juvenile idiopathic arthritis (JIA) can impact physical function.
- Understanding energy system development in JIA is crucial for rehabilitation.
Purpose of the Study:
- To compare the anaerobic-to-aerobic power ratio in children with JIA versus healthy controls.
- To investigate factors influencing this ratio in pediatric populations.
Main Methods:
- Cross-sectional study involving 62 children with JIA and 50 healthy children.
- Anaerobic power assessed via Wingate Anaerobic Exercise Test.
- Aerobic power measured using cardiopulmonary exercise testing.
Main Results:
- No statistically significant differences in mean or peak anaerobic-to-aerobic power ratios were found between children with JIA and healthy peers.
- These findings remained consistent after adjusting for age, height, and body mass.
- No significant differences were observed across JIA onset types, sexes, or between JIA patients and controls over time.
Conclusions:
- The development of the anaerobic-to-aerobic power ratio is comparable in children with JIA and healthy children.
- Interval training for anaerobic capacity and aerobic exercise training are recommended for JIA management.
Objective:
To examine the anaerobic-to-aerobic power ratio in children with juvenile idiopathic arthritis (JIA) compared with healthy peers.
Methods:
Sixty-two patients with JIA (mean +/- SD age 11.9 +/- 2.1 years, range 7.2-15.9 years) with varying severity of disease and 50 healthy children (mean +/- SD age 12.1 +/- 2.1, range 8.4-15.9 years) participated in this study. Anaerobic power was measured using the Wingate Anaerobic Exercise Test. Aerobic power was measured using a cardiopulmonary exercise test. The power ratio was calculated as the ratio between the anaerobic mechanical power and aerobic mechanical power in watts.
Results:
Mean +/- SD anaerobic-to-aerobic power ratio and peak anaerobic-to-aerobic ratios in children with JIA were 1.98 +/- 0.51 and 3.28 +/- 1.15, respectively. Compared with healthy children these differences were not statistically significant (P = 0.52 and P = 0.99, respectively). The differences in these ratios were not statistically significant when corrected for age, height, and body mass. Statistical analyses showed no significant difference between disease-onset types of JIA for mean anaerobic-to-aerobic power ratio and peak anaerobic-to-aerobic ratio, respectively. Furthermore, there was no significant difference in the development of the power ratios between children with JIA and healthy controls, or between girls and boys.
Conclusion:
This cross-sectional study suggests that the development of the anaerobic-to-aerobic power ratio is not statistically different in children with JIA compared with healthy peers. Exercise training of the anaerobic capacity through interval training, along with aerobic exercise training, seems warranted in the exercise therapy programs of children with JIA.
More Related Videos
08:21Non-invasive Assessments of Subjective and Objective Recovery Characteristics Following an Exhaustive Jump Protocol
Published on: June 8, 2017
09:18Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
Related Concept Videos
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Chronic Obstructive Pulmonary Disease II: Emphysema