Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Correlations between periodontal tissue breakdown and cell populations.

U E Zappa1, A M Polson, M A Espeland

  • 1Department of Periodontology, Eastman Dental Center, Rochester, New York.

Schweizer Monatsschrift Fur Zahnmedizin = Revue Mensuelle Suisse D'Odonto-Stomatologie = Rivista Mensile Svizzera Di Odontologia E Stomatologia
|January 1, 1991
PubMed
Summary

This study found that polymorphonuclear leucocytes (PMNs) strongly correlate with periodontal tissue destruction. Increased PMN levels indicate their significant role in acute bursts of periodontitis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The relationship between repeated measurements of HbA<sub>1c</sub> and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study.

Cardiovascular diabetology·2024
Same author

Erratum to: Association between Modifiable Risk Factors and Levels of Blood-Based Biomarkers of Alzheimer's and Related Dementias in the Look AHEAD Cohort.

JAR life·2024
Same author

Association between Modifiable Risk Factors and Levels of Blood-Based Biomarkers of Alzheimer's and Related Dementias in the Look AHEAD Cohort.

JAR life·2024
Same author

Daytime Sleepiness Is Associated with Lower Cognitive Scores: The Look AHEAD Study.

JAR life·2023
Same author

Interactions between estradiol, diabetes, and brain aging and the risk for cognitive impairment.

Climacteric : the journal of the International Menopause Society·2021
Same author

Sustaining eHealth engagement in a multi-year weight gain prevention intervention.

Obesity science & practice·2019

Area of Science:

  • Periodontology
  • Immunology
  • Cell Biology

Background:

  • Periodontitis involves significant periodontal tissue destruction.
  • The role of specific immune cells in this process requires further elucidation.

Purpose of the Study:

  • To evaluate the correlation between periodontal breakdown and specific cell populations during experimental periodontitis.
  • To investigate the role of polymorphonuclear leucocytes (PMNs) in acute periodontal tissue destruction.

Main Methods:

  • Experimental periodontitis was induced in squirrel monkeys using silk ligatures.
  • Periodontal destruction was assessed by measuring connective tissue attachment and alveolar bone loss.
  • Cell populations, including PMNs and plasma cells, were quantified at various time points.

Related Experiment Videos

Main Results:

  • Statistically significant loss of connective tissue attachment and crestal alveolar bone was observed.
  • A significant increase in total cell counts and PMNs was noted compared to baseline.
  • Periodontal tissue destruction showed a strong positive correlation with the number of PMNs.

Conclusions:

  • Polymorphonuclear leucocytes (PMNs) play a crucial role in acute periodontal tissue destruction.
  • The findings highlight the potential involvement of PMNs in the inflammatory processes of periodontitis.