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Updated: Jun 22, 2026
A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
Published on: November 6, 2015
Functional outcomes after limb-salvage surgery and endoprosthetic reconstruction with an expandable prosthesis: a
Kathleen Beebe1, Kimberly J Song, Ellen Ross
1Department of Orthopaedics, University of Medicine and Dentistry of New Jersey, Newark, NJ 07305, USA. beebeka@umdnj.edu
Insights
Noninvasive expandable endoprostheses in pediatric bone cancer patients showed satisfactory functional outcomes, with good emotional acceptance despite some persistent gait and mobility challenges. This offers a viable limb-sparing option for young patients.
Area of Science:
- Orthopedic Oncology
- Pediatric Orthopedics
- Biomedical Engineering
Background:
- Pediatric bone tumors often necessitate limb-sparing surgery.
- Expandable endoprostheses offer a noninvasive solution for growing bone replacements.
Observation:
- Four pediatric patients with bone tumors underwent femur/tibia replacement using expandable endoprostheses.
- Functional outcomes were assessed using MSTS scores, SF-36, gait analysis, sit-to-stand transitions, and range of motion (ROM).
Findings:
- Patients reported satisfactory mental health and high emotional acceptance.
- Physical limitations included decreased ROM, strength, altered gait, and sit-to-stand patterns.
- SF-36 physical scores were below national averages, while mental scores were satisfactory.
Implications:
- Noninvasive expandable endoprostheses provide acceptable functional and emotional outcomes for pediatric bone tumor patients.
- Addressing persistent physical deficits is crucial for optimizing long-term function.
- This approach supports limb salvage and improves quality of life in young cancer survivors.
Objective:
To determine the functional outcomes of skeletally immature patients after replacement of the femur and tibia performed by using noninvasive expandable endoprostheses.
Design:
Case series.
Setting:
A hospital-based ambulatory care center.
Participants:
Pediatric patients (N=4) with primary bone tumors of the distal femur and proximal tibia who underwent surgical replacement performed by using the Repiphysis noninvasive expandable endoprosthesis (Wright Medical Technology, Memphis, TN).
Interventions:
Wide resection of bone sarcoma and placement of expandable endoprosthesis.
Main Outcome Measures:
Musculoskeletal Tumor Society (MSTS) scores were assessed at the beginning of the study and at each follow-up visit. Medical Outcomes Study 36-Item Short-Form Health Survey, Version 2 (SF-36); gait; sit-to-stand transition; and range of motion (ROM) were assessed at an average follow-up of 31.5 months.
Results:
At an average of 31.5 months postoperative, the SF-36 physical component summary scores lagged behind the national mean, whereas the mental component summary scores were satisfactory. MSTS scores indicated low levels of pain and supports use with high emotional acceptance and walking ability but persisting difficulties with function and gait. Patients also showed altered patterns of sit-to-stand transition including decreased peak vertical force in the operated limb and increased center of mass momentum in a shorter amount of time. Parts of gait functioning were found to be decreased, including gait velocity, stride length, and cadence. Some patients displayed alternate weight-bearing strategies that accompanied increased double-limb support and stance phase during walking. ROM and strength were diminished at both the hip and knee joints in the operated limb and in the nonoperated limb.
Conclusions:
Reconstruction with a noninvasive expandable endoprosthesis produces satisfactory functional outcomes in pediatric patients with primary tumors of the bone. Patients in our study displayed some persisting physical difficulties including decreased ROM and strength and altered gait and sit-to-stand patterns, yet they maintained high levels of emotional acceptance and coping.
