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Updated: Jun 10, 2026

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Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
Published on: December 22, 2014
A perspective: metatranscriptomics as a tool for the discovery of novel biocatalysts
1DOE Joint Genome Institute, Microbial Ecology Program, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA. FWarnecke@lbl.gov
Journal of Biotechnology
|June 2, 2009
Abstract:
In this mini-review, advantages and current bottlenecks of metatranscriptomic-sequencing for the discovery of novel enzymes for biotechnological applications will be discussed. Comparison of this innovative approach to traditional metagenomic-sequencing will illustrate that expression profiling has a promising future as a direct and very efficient method for the discovery of novel biocatalysts, even from complex microbial communities.

