Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Applying the consensus-based salivary glands ultrasound scoring system in lacrimal glands: results of a static image-based OMERACT reliability exercise.

Seminars in arthritis and rheumatism·2026
Same author

Plain language summary: gout remission with pegloticase.

Therapeutic advances in musculoskeletal disease·2026
Same author

Gout Remission With Pegloticase-Induced Intensive Urate-Lowering Therapy: A Post Hoc Clinical Trial Analysis.

ACR open rheumatology·2025
Same author

Scoping literature review to identify candidate domains for the OMERACT Systemic Lupus Erythematosus core outcome set.

Seminars in arthritis and rheumatism·2025
Same author

Telescoping Fingers in Arthritis Mutilans.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2025
Same author

Musculoskeletal Ultrasound Practices of Graduates of a Blended-Learning Program: A Survey of Rheumatologists From the United States.

Arthritis care & research·2024
Same journal

Bridging the Divide in Global Rheumatology.

Rheumatic diseases clinics of North America·2026
Same journal

Foreword.

Rheumatic diseases clinics of North America·2026
Same journal

Pulmonary Complications of Biological Therapies in Inflammatory and Autoimmune Diseases.

Rheumatic diseases clinics of North America·2026
Same journal

Artificial Intelligence and Social Determinants of Health.

Rheumatic diseases clinics of North America·2026
Same journal

Updates in Ultrasound in Rheumatology.

Rheumatic diseases clinics of North America·2026
Same journal

Health Systems Strengthening to Promote Access to Care for Rheumatic and Musculoskeletal Diseases Globally.

Rheumatic diseases clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Soft tissue infections.

Karina D Torralba1, Francisco P Quismorio

  • 1Division of Rheumatology, Department of Internal Medicine, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 711, Los Angeles, CA 90033, USA. ktorrabl@usc.edu

Rheumatic Diseases Clinics of North America
|June 2, 2009
PubMed
Summary
This summary is machine-generated.

Patients with rheumatic diseases face higher risks of potentially fatal soft tissue infections. Prompt diagnosis and treatment, including antibiotics and surgery, are crucial for managing these infections.

Related Experiment Videos

Last Updated: Jun 22, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Area of Science:

  • Infectious diseases
  • Rheumatology
  • Immunology

Background:

  • Soft tissue infections pose significant morbidity and mortality risks, particularly in individuals with rheumatic diseases.
  • Rheumatic disease patients may have increased susceptibility due to immunologic defects, genetic factors, and immunomodulatory therapies like biologic agents.
  • Effective management necessitates prompt diagnosis and intervention with antibiotics and potentially surgical procedures.

Purpose of the Study:

  • To review recent literature on soft tissue infections in patients with rheumatic diseases.
  • To examine the presentation and clinical course of specific infections including infectious tenosynovitis, septic bursitis, pyomyositis, and necrotizing fasciitis.
  • To highlight the unique considerations for managing these infections in the context of rheumatic conditions.

Main Methods:

  • Literature review of recent publications.
  • Analysis of clinical presentations and disease progression.
  • Focus on infectious tenosynovitis, septic bursitis, pyomyositis, and necrotizing fasciitis.

Main Results:

  • Soft tissue infections are common and life-threatening in rheumatic disease patients.
  • Immunomodulatory therapies, including biologics, may increase infection risk.
  • Timely diagnosis and treatment are essential for favorable outcomes.

Conclusions:

  • Rheumatic disease patients require vigilant monitoring for soft tissue infections.
  • Understanding the specific risks and presentations is key for effective management.
  • Integrated approaches involving antibiotics and surgery are vital for resolving these infections.