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Updated: Jun 22, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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Hand osteoarthritis: an epidemiological perspective.

Leonid Kalichman1, Gabriela Hernández-Molina

  • 1Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel. kleonid@bgu.ac.il

Seminars in Arthritis and Rheumatism
|June 2, 2009
PubMed
Summary

Hand osteoarthritis (OA) is common, especially in women over 50. Risk factors include genetics, age, and manual labor, impacting daily tasks.

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Area of Science:

  • Rheumatology
  • Epidemiology
  • Orthopedics

Background:

  • Hand osteoarthritis (OA) is a prevalent condition with diverse clinical presentations.
  • It significantly impacts hand function and daily activities.

Purpose of the Study:

  • To review the prevalence of hand OA.
  • To examine the impact of hand OA on function.
  • To identify various risk factors associated with hand OA.

Main Methods:

  • Searched PubMed and MEDLINE databases (1950-2009).
  • Keywords included "hand," "hand osteoarthritis," and specific joint names.
  • Included cohort, cross-sectional, and case-control studies on epidemiology, clinical features, functional impairment, and risk factors.

Main Results:

  • Hand OA is heterogeneous, age- and gender-dependent, affecting women over 50 more frequently.
  • Radiographic hand OA prevalence reaches 80% in the elderly.
  • Strong genetic predisposition exists, alongside factors like manual labor, weight, smoking, and joint hyperlaxity.

Conclusions:

  • Multiple risk factors for hand OA are identified, but their interrelationships require further understanding.
  • There is a need for developing preventive strategies and defining future research goals.