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Published on: February 9, 2021
Complications of hypercalciuria
Andrew Schwaderer1, Tarak Srivastava
1Division or Nephrology, Nationwide Children's Hospital, The Ohio State University, 700 Children's Drive, Columbus, OH 43205, USA. schwadea@pediatrics.ohio-state.edu
Insights
Idiopathic hypercalciuria in children can cause various symptoms like kidney stones and pain. This review covers calcium metabolism, hypercalciuria types, consequences, and management strategies.
Area of Science:
- Pediatric Nephrology
- Metabolic Disorders
Background:
- Idiopathic hypercalciuria is a frequent pediatric condition.
- It manifests with diverse clinical signs including hematuria, voiding dysfunction, pain, nephrolithiasis, UTIs, and reduced bone density.
Purpose of the Study:
- To provide a concise review of idiopathic hypercalciuria in children.
- To cover calcium metabolism, clinical presentations, and evaluation/management approaches.
Main Methods:
- Literature review of idiopathic hypercalciuria in pediatric populations.
- Synthesis of information on calcium metabolism and clinical consequences.
- Outline of diagnostic and therapeutic strategies.
Main Results:
- Idiopathic hypercalciuria presents a spectrum of clinical issues in children.
- Understanding calcium metabolism is key to managing this disorder.
- A systematic approach to evaluation and treatment is essential.
Conclusions:
- Idiopathic hypercalciuria requires comprehensive understanding and management in pediatric care.
- Early diagnosis and intervention can mitigate long-term complications.
- This review offers a foundational guide for clinicians.
Abstract:
Idiopathic hypercalciuria is a common disorder in children and can present with a range of clinical presentations such as hematuria, voiding dysfunction, flank pain, abdominal pain, nephrolithiasis, urinary tract infection and decreased bone mineral density. In the review below we provide a brief overview of calcium metabolism, types and clinical consequences of hypercalciuria and a brief approach to evaluation and management of hypercalciuria.
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