Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reduced Image Quality Impairs Monocular Blur-Driven Accommodation in Keratoconus.

Investigative ophthalmology & visual science·2026

Same author

Effect of spherical aberration on the vergence-accommodation conflict.

Biomedical optics express·2026

Same author

Comparison of decentration, tilt, and dynamic stability between retropupillary iris claw and scleral fixated intraocular lenses with flanged haptics.

Journal of cataract and refractive surgery·2026

Same author

Impact of Myopia Control Spectacles on Retinal Image Contrast.

Investigative ophthalmology & visual science·2026

Same author

Optical quality and anisotropy across the retina of Chinese children's eyes.

Journal of the Optical Society of America. A, Optics, image science, and vision·2026

Same author

Stiles-Crawford effect in infrared two-photon vision.

Biomedical optics express·2026

Search research articles

Related Experiment Video

Updated: Jun 22, 2026

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

Adaptive optics with a programmable phase modulator: applications in the human eye.

Pedro Prieto, Enrique Fernández, Silvestre Manzanera

|June 2, 2009

Summary

A novel adaptive optics system using a liquid crystal spatial light modulator effectively corrects human eye aberrations. This technology offers precise aberration generation and correction for vision research and potential visual enhancement.

More Related Videos

Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping

Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping

Published on: March 20, 2017

Characterization of SiN Integrated Optical Phased Arrays on a Wafer-Scale Test Station

Characterization of SiN Integrated Optical Phased Arrays on a Wafer-Scale Test Station

Published on: April 1, 2020

Related Experiment Videos

Last Updated: Jun 22, 2026

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping

Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping

Published on: March 20, 2017

Characterization of SiN Integrated Optical Phased Arrays on a Wafer-Scale Test Station

Characterization of SiN Integrated Optical Phased Arrays on a Wafer-Scale Test Station

Published on: April 1, 2020

Area of Science:

Ophthalmology
Optical Engineering
Biomedical Optics

Background:

Adaptive optics (AO) systems are crucial for high-resolution retinal imaging and vision correction.
AO systems can also generate specific ocular aberrations for visual function research.

Purpose of the Study:

To develop and evaluate a prototype AO system using a liquid crystal spatial light modulator (LCSLM).
To assess the LCSLM's capability as both an aberration generator and corrector for the human eye.

Main Methods:

A prototype AO system was built using a Hamamatsu Programmable Phase Modulator X8267.
The system employed red (633nm) or infrared (780nm) illumination and a Hartmann-Shack wavefront sensor (25 Hz).
Aberration generation was tested using single Zernike terms; correction was demonstrated on an artificial eye and in living human eyes.

Main Results:

The LCSLM demonstrated linear aberration generation with minimal cross-coupling between Zernike terms.
Single-step aberration correction was achieved for an artificial eye.
Successful closed-loop aberration correction was performed on living human eyes.

Conclusions:

The developed LCSLM-based AO system can generate and compensate for a wide range of ocular aberrations.
Despite a slower temporal response than deformable mirrors, the LCSLM offers advantages in effective stroke and mode independence.
This technology holds promise for advanced vision research and potential therapeutic applications.