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Updated: Jun 22, 2026

Transauricular Vagus Nerve Stimulation and Electroencephalographic Assessment in Disorders of Consciousness
Published on: July 11, 2025
[Holter monitoring and programmed ventricular stimulation]
1Abteilung für Kardiologie Medizinische Klinik, St. Vincentius Krankenhäuser, Edgar-von-Gierke-Strasse 2, 76135, Karlsruhe.
Abstract:
Long-term ECG recordings are the method of choice to evaluate quantity and quality of spontaneous rhythm disturbances. However, this method is limited by the variability of the arrhythmias. Invasive procedures such as programmed stimulation allow the provocation of tachyarrhythmias. Indications for both methods are diagnostic clarification of clinical symptoms, risk stratification with respect to arrhythmogenic sudden cardiac death as well as the control of antiarrhythmic therapy.Due to the high variability of spontaneous complex ventricular arrhythmias, Holter monitoring often fails to document the cause of severe symptoms such as syncope or sudden cardiac death. In these patients, invasive electrophysiological testing is required to provoke the arrhythmia.The prognostic significance of spontaneous ventricular arrhythmias recorded during ambulatory monitoring depends on the underlying cardiac disease. In patients with coronary artery disease and a history of myocardial infarction there is evidence that frequent single and/or complex ventricular extrasystoles indicate an increased risk of sudden cardiac death, especially in the presence of a reduced left ventricular function. In these patients, programmed ventricular stimulation can further characterize a highrisk group.For the management of antiarrhythmic therapy in symptomatic patients, under certain conditions both methods appear to be helpful. For the majority of these patients, however, the invasive electrophysiologic study should be preferred.Thus, long-term ECG recordings and programmed electrical stimulation are no competing, but complementary methods in clinical cardiology.
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