Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nationwide Detection and Molecular Characterization of Hepatitis E Virus RNA in Retail Pork Meat in Japan.

Viruses·2026
Same author

2024 survey of the frequency of fixed-combination eye drop use by patients with glaucoma at multiple private practices in Japan.

Japanese journal of ophthalmology·2026
Same author

Relationship between pre-pregnancy body mass index and postpartum depression, and the mediation effects of cesarean delivery, low birth weight, child anomaly, and breastfeeding: a prospective birth cohort in the Japan environment and children's study.

BMC pregnancy and childbirth·2026
Same author

Early macular choroidal hemodynamic changes after faricimab loading in treatment-naïve diabetic macular edema.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Medical School Type and Rural Practice among Japanese Internal Medicine Physicians: Analysis of 2018-2022 National Census Data.

The Tohoku journal of experimental medicine·2026
Same author

Choroidal Thickening and Reduced Macular Blood Flow in Children with Hyperopic Anisometropic Amblyopia.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jun 22, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Idiopathic macular hole vitrectomy without postoperative face-down positioning.

Fumihiko Yagi1, Yukihiro Sato, Seiji Takagi

  • 1Second Department of Ophthalmology, Toho University School of Medicine, Faculty of Medicine, Tokyo, Japan. fyagi@med.toho-u.ac.jp

Japanese Journal of Ophthalmology
|June 2, 2009
PubMed
Summary

Vitrectomy with internal limiting membrane (ILM) peeling and SF(6) gas tamponade effectively treats macular holes without requiring face-down positioning. This procedure leads to high closure rates and significant visual acuity improvement.

More Related Videos

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery
04:36

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

A Step by Step Protocol for Subretinal Surgery in Rabbits
12:31

A Step by Step Protocol for Subretinal Surgery in Rabbits

Published on: September 13, 2016

Related Experiment Videos

Last Updated: Jun 22, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery
04:36

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

A Step by Step Protocol for Subretinal Surgery in Rabbits
12:31

A Step by Step Protocol for Subretinal Surgery in Rabbits

Published on: September 13, 2016

Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Retinal Surgery

Background:

  • Macular holes are a significant cause of vision loss.
  • Traditional surgical repair often necessitates prolonged face-down positioning, impacting patient comfort and adherence.
  • Developing alternative surgical techniques is crucial for improving patient outcomes.

Purpose of the Study:

  • To assess the efficacy of pars plana vitrectomy with internal limiting membrane (ILM) peeling and sulfur hexafluoride (SF(6)) gas tamponade for macular hole repair.
  • To evaluate outcomes in patients not requiring face-down positioning post-surgery.

Main Methods:

  • Pars plana vitrectomy with indocyanine green-assisted ILM peeling and 20% SF(6) gas tamponade was performed on 21 eyes.
  • Macular hole closure was assessed using biomicroscopy and optical coherence tomography.
  • Preoperative and postoperative visual acuities (VAs) were compared.

Main Results:

  • The study included various stages of macular holes (2, 3, and 4), with a mean hole size of 0.35 disc diameters.
  • An initial closure rate of 90.5% was observed, with a final closure rate of 100% and no reopening.
  • Significant improvement in mean VA was noted, from 0.65 preoperatively to 0.42 at 3 months post-surgery (P < 0.0001).

Conclusions:

  • Vitrectomy with ILM peeling and SF(6) gas tamponade is an effective treatment for macular holes.
  • This technique achieves favorable anatomical closure and functional visual recovery without the need for face-down positioning.
  • The procedure offers a promising alternative for macular hole surgery, enhancing patient comfort and compliance.