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Updated: Jun 22, 2026

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults
Published on: February 12, 2020
Modifying postural adaptation following a CVA through prismatic shift of visuo-spatial egocenter
William V Padula1, Christine A Nelson, William V Padula
1Padula Institute of Vision, 37 Soundview Road, Guilford, CT 06437, USA. wpadula@padulainstitute.com
Objective:
To demonstrate that Visual Midline Shift Syndrome (VMSS) following a cerebrovascular accident (CVA) can be corrected with yoked prisms.
Research Design:
This randomized study describes how the use of yoked prisms affects visual midline and documents the influence of yoked prisms on improving postural orientation.
Methods And Procedures:
Evaluation of VMSS and its correlation with postural lean during ambulation were studied in 30 post-CVA subjects and 30 controls.
Experimental Interventions:
Yoked prisms were used to treat VMSS by correcting posture and balance.
Outcomes And Results:
Over 50% of post-CVA subjects showed positive visual midline shift (p < 0.001; 95% confidence interval [CI], 0.660.93 for right CVAs and p = 0.001; 95% CI, 0.61-0.93 for left CVAs). A statistically significant proportion of those with a positive shift showed a decrease in shift utilizing yoked prisms (p < 0.001; 95% CI, 0.73-0.97 for right CVAs and p = 0.001; 95% CI, 0.07-0.39 for left CVAs). Additionally, over 50% of CVA subjects developed lean or drift away from hemiparesis and many subjects showed increased weight-bearing on the hemiparetic side with yoked prisms.
Conclusions:
Yoked prisms are an effective means of treating VMSS in this population and may be useful in other neurological syndromes with visuo-spatial involvement.
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