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Metabolic control of TYPE 1 Diabetes in children treated with insulin pump therapy

Snijezana Hasanbegović1, Edo Hasanbegović

  • 1Paediatric Clinic, University of Sarajevo Clinics Centre, Sarajevo, Bosnia and Herzegovina.

Bosnian Journal of Basic Medical Sciences
|June 3, 2009
PubMed

Insights

Insulin pump (IP) therapy significantly improves metabolic control in children with Type 1 Diabetes Mellitus (T1DM), reducing HbA1c levels and lowering risks of long-term complications.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Metabolic Disorders

Background:

  • Type 1 Diabetes Mellitus (T1DM) requires continuous metabolic monitoring.
  • Insulin pump (IP) therapy is an advanced treatment option for T1DM.
  • Effective metabolic control is crucial to prevent T1DM complications.

Purpose of the Study:

  • To evaluate the efficacy of insulin pump (IP) therapy in improving metabolic control in children with T1DM.
  • To assess changes in glycosylated hemoglobin (HbA1c) levels before and after initiating IP therapy.
  • To determine if IP therapy helps achieve therapeutic goals for T1DM management.

Main Methods:

  • Retrospective study of T1DM patients using IP therapy at a Paediatric Clinic.
  • Analysis of patient demographics, prior diabetes management, and HbA1c levels.
  • Comparison of HbA1c values before and 6 months after IP therapy initiation.

Main Results:

  • A total of 39 children (61.5% boys) with T1DM were included.
  • Mean HbA1c decreased from 8.57% before IP therapy to 7.53% after 6 months (p=0.0009).
  • Significant improvement in metabolic control was observed, with 7.53% HbA1c indicating progress towards the <7.0% therapeutic goal.

Conclusions:

  • Insulin pump therapy is highly effective in improving glycemic control in pediatric T1DM patients.
  • Achieving lower HbA1c levels with IP therapy can mitigate the risk of microvascular complications.
  • IP therapy represents an efficient treatment strategy for managing T1DM in children.

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