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Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...

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Related Experiment Video

Updated: Jun 22, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

Endoscopic band ligation could decrease recurrent bleeding in Mallory-Weiss syndrome as compared to haemostasis by

S Lecleire1, M Antonietti, I Iwanicki-Caron

  • 1Gastroenterology Department, Digestive Endoscopy Unit, Rouen University Hospital, Rouen Cedex, France. stephane.lecleire@churouen.fr

Alimentary Pharmacology & Therapeutics
|June 3, 2009
PubMed
Summary
This summary is machine-generated.

Endoscopic band ligation is more effective than hemoclips plus epinephrine for Mallory-Weiss syndrome bleeding. Hemoclips with epinephrine increase the risk of recurrent bleeding, suggesting band ligation as a preferred treatment.

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Last Updated: Jun 22, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

Area of Science:

  • Gastroenterology
  • Endoscopic interventions
  • Hemorrhage control

Background:

  • Mallory-Weiss syndrome (MWS) can cause active bleeding requiring endoscopic hemostasis.
  • Current endoscopic hemostasis modalities for MWS are not well-defined.

Purpose of the Study:

  • To compare the efficacy of endoscopic band ligation versus hemoclip plus epinephrine (adrenaline) for bleeding MWS.

Main Methods:

  • A retrospective study of 56 patients with active bleeding MWS from 2001-2008.
  • 29 patients underwent band ligation; 27 received hemoclip plus epinephrine.
  • Efficacy and early recurrent bleeding were compared between groups.

Main Results:

  • Primary hemostasis was achieved in all patients.
  • Recurrent bleeding occurred in 0% of the band ligation group versus 18% in the hemoclip plus epinephrine group (P=0.02).
  • Hemoclips plus epinephrine and active bleeding were independent predictors of recurrent bleeding.

Conclusions:

  • Hemostasis with hemoclips plus epinephrine is an independent predictor of rebleeding in MWS.
  • Band ligation may be the preferred initial endoscopic treatment for bleeding MWS.
  • Further prospective studies are needed to confirm these findings.