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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Simple evaluation of aortic arch calcification by chest radiography in hemodialysis patients
Tetsuya Ogawa1, Hideki Ishida, Nami Matsuda
1Department of Medicine, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan. togawa@kc.twmu.ac.jp
Insights
A simple chest X-ray score for aortic arch calcification (AoAC) is a reliable, noninvasive method to assess vascular calcification in hemodialysis patients. This in-office technique correlates well with CT scans, aiding treatment decisions.
Area of Science:
- Nephrology
- Radiology
- Cardiovascular Medicine
Background:
- Vascular calcification is a significant predictor of poor outcomes in patients undergoing chronic hemodialysis (HD).
- Computed tomography (CT) is a standard method for quantifying aortic arch calcification volume (AoACV), but it is resource-intensive.
- Simple, noninvasive in-office techniques are needed for assessing vascular calcification in HD patients.
Purpose of the Study:
- To compare a simple, noninvasive semiquantitative technique for aortic arch calcification scoring (AoACS) with multidetector CT-based AoACV measurement.
- To evaluate the utility of AoACS as an in-office imaging tool for HD patients.
Main Methods:
- Sixty-three maintenance HD patients were enrolled.
- Aortic arch calcification was semiquantitatively assessed using an AoAC score (AoACS) on plain chest radiography.
- AoACV was measured using multidetector CT.
Main Results:
- The mean AoACV was 6.6% (range 0%–36.5%).
- AoACS demonstrated a high correlation with AoACV (r=0.635, P<0.001).
- Age and pulse pressure were identified as significant independent determinants of AoACS.
Conclusions:
- A simple AoACS measurement on plain chest radiography is a reliable and noninvasive method for assessing aortic arch calcification in HD patients.
- This in-office technique may be valuable for guiding therapeutic strategies in this population.
Abstract:
Vascular calcification is associated with a poor prognosis in dialysis patients. It can be assessed with computed tomography but simple inoffice techniques may provide useful information. We compared the results obtained with a simple noninvasive technique with those obtained using multidetector computed tomography for aortic arch calcification volume (AoACV) in chronic hemodialysis (HD) patients. The enrolled study subjects were 63 (32 men and 31 women) maintenance HD patients. Calcification of the aortic arch was semiquantitatively estimated with a AoAC score (AoACS) on plain chest radiology. The AoACV was increased, with a mean value of 6.6 ranging from 0% to 36.5%. The coefficient of intraobserver variation was less than 2.5%. Aortic arch calcification score was highly correlated with AoACV (r=0.635, P<0.001). Multiple regression analysis showed age (F value=12.62, P<0.001) and pulse pressure (F value=4.54, P=0.037) to be significant independent determinants of AoACS. In conclusion, a simple measurement of AoACS may be useful for inoffice imaging to choose a therapeutic regimen in HD patients.
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