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Does the ribosome have initiation and elongation modes of translation?
Tanel Tenson1, Vasili Hauryliuk
1Institute of Technology, University of Tartu, Nooruse 1, Tartu 50411, Estonia. tanel.tenson@ut.ee
Molecular Microbiology
|June 3, 2009
Abstract:
RNA polymerases differ functionally and structurally in the initiation phase of transcription, when polymerization of 8-12 nucleotides occurs, from the later phases of transcription. Here we argue that the ribosome also might have different properties when translating the first codons in open reading frames, as compared with the later phases of translation.
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