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Updated: Aug 3, 2026

Murine Prostate Micro-dissection and Surgical Castration
Published on: May 11, 2016
Activities of the androgen-responsive receptor of the prostatic plasma membrane
Abstract:
Evidence of the presence of an androgen-activated "gatekeeper" receptor in the human prostate plasma membrane is presented. Not only does testosterone in vitro very rapidly accelerate uptake of alpha-aminoisobutyric acid into prostate slices but also its metabolite, dihydrotestosterone, greatly increases the rates of phosphorylation and dephosphorylation of the cation-dependent ATPase of isolated membranes. The relationship of this regulatory unit to prostatic physiologic processes is discussed.
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