Related Experiment Videos
Porocarcinoma: a rare sweat gland malignancy
Asghar H Asghar1, Humera Mahmood, Mohammad Faheem
1Department of Radiotherapy, NORI Hospital, Islamabad. quaidian@yahoo.com
Summary
Eccrine Porocarcinoma (ECP), a rare sweat gland cancer, can present as a fungating growth. This case report details a 52-year-old male diagnosed with ECP on his pre-auricular region.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Eccrine Porocarcinoma (ECP) is a rare malignant neoplasm originating from the intraepithelial sweat gland ducts.
- ECP presents with various synonyms including malignant hidroacanthoma simplex and sweat gland carcinoma.
- Standard treatment involves wide local excision, with chemotherapy for metastatic disease.
Observation:
- A 52-year-old male presented with a fungating mass on the left pre-auricular area.
- The lesion's appearance prompted further investigation.
Findings:
- Histopathological examination confirmed the diagnosis of Eccrine Porocarcinoma.
- The tumor's location was the left pre-auricular region.
Implications:
- This case highlights the importance of histopathological diagnosis for rare skin malignancies like ECP.
- Early detection and appropriate management are crucial for patient outcomes.
- Further research into ECP treatment modalities may be warranted.
Related Concept Videos
02:23Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
02:23Abnormal Proliferation
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
01:20Accessory Structures of the Skin: Sweat Glands
Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
02:21Cancers Originate from Somatic Mutations in a Single Cell
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
02:21Cancers Originate from Somatic Mutations in a Single Cell
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...