Related Experiment Video
Updated: Jun 22, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Adaptation and development of software simulation methodologies for cardiovascular engineering: present and future
V Díaz-Zuccarini1, A J Narracott, G Burriesci
1Cardiovascular Engineering and Medical Devices Group, Department of Mechanical Engineering, University College London, Torrington Place, London WC1 7JE, UK. v.diaz@ucl.ac.uk
Abstract:
This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective.

