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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Validity of self-reported comorbidities in systemic sclerosis.

Marie Hudson1, Anish Sharma, Jessica Bernstein

  • 1Sir Mortimer B. Davis-Jewish General Hospital and McGill University, Montreal, Quebec H3T 1E2, Canada. marie.hudson@mcgill.ca

The Journal of Rheumatology
|June 3, 2009
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Patient self-reports of chronic conditions in systemic sclerosis (SSc) lack accuracy. Chart review reveals low sensitivity and variable positive predictive values for conditions like hypertension, diabetes, and cancer.

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Area of Science:

  • Rheumatology
  • Clinical Epidemiology
  • Patient-Reported Outcomes

Background:

  • Systemic sclerosis (SSc) is a complex autoimmune disease.
  • Accurate assessment of comorbidities is crucial for managing SSc patients.
  • Self-reported health data is increasingly used but requires validation.

Purpose of the Study:

  • To evaluate the accuracy of self-reported common chronic conditions in SSc patients.
  • To compare patient self-reports against medical chart reviews for five specific comorbidities.

Main Methods:

  • A study involving 130 SSc patients at a major referral hospital.
  • Patients self-reported the presence of hypertension, diabetes, cancer, depression, and osteoarthritis/back pain.
  • Medical records were reviewed to validate self-reported diagnoses, calculating sensitivity, specificity, and positive predictive values.

Main Results:

  • Self-reported data for 130 SSc patients were compared to chart reviews.
  • Sensitivity for self-reported conditions ranged from 35% (cancer) to 86% (diabetes).
  • Specificity was generally moderate to high (76%–99%), while positive predictive values varied (31%–86%).

Conclusions:

  • Self-reported comorbidities in SSc patients are not sufficiently accurate for identifying common chronic conditions.
  • Relying solely on self-reports may lead to misidentification or underdiagnosis of significant health issues in SSc.
  • Further research into validated screening tools for SSc comorbidities is warranted.