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Pathogenesis of holoprosencephaly.

Xin Geng1, Guillermo Oliver

  • 1Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

The Journal of Clinical Investigation
|June 3, 2009
PubMed
Summary

Holoprosencephaly (HPE) is a common forebrain malformation with diverse causes. Mouse models have illuminated molecular factors and variable pathology, guiding future research into unanswered questions about HPE.

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