Related Experiment Video
Updated: Jun 22, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
Cardiac myxoma showing extramedullary hematopoiesis in a patient with beta thalassemia
Rene Joukhadar1, Luis E De Las Casas, Omosalewa Lalude
1Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA. rene.joukhadar@ttuhsc.edu
Abstract:
A 52-year-old woman presented with recurrent episodes of chest pain, shortness of breath, palpitations, and fatigue for three months. Her past medical history was significant for chronic anemia. Physical examination revealed a pansystolic murmur radiating to the left axilla. Her admission workup showed microcytic anemia. Her serum creatinine and iron studies were within normal limits and her hemoglobin electrophoresis pattern was that of beta thalassemia minor. Two-dimensional echocardiography showed a multilobulated mobile mass attached to the mitral annulus at the base of the anterior mitral valve leaflet. The patient underwent surgical resection of the mass. Pathology examination revealed a cardiac myxoma with conspicuous foci of extramedullary hematopoiesis.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Mitral Stenosis II: Clinical features and Diagnostic Tests
Hematopoiesis

