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Updated: Jun 22, 2026
08:13
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
[Noncompaction of the left ventricular myocardium]
Sahrai Saeed1, Johnny Vegsundvåg, Inge Lode
1Medisinsk avdeling, Alesund sjukehus, 6026 Alesund. sahrai.saeed@helse-sunnmore.no
Summary
Left ventricular noncompaction is a heart muscle disorder that can cause dysfunction and serious complications. Early diagnosis is crucial for effective patient management and improved outcomes.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Medical Diagnostics
Background:
- Left ventricular noncompaction is a recently identified cause of left ventricular dysfunction.
- This condition can manifest clinically at any age, presenting diverse epidemiological and clinical aspects.
Purpose of the Study:
- To describe the epidemiological and clinical aspects of left ventricular noncompaction.
- To highlight the importance of recognizing this condition for patient management.
Main Methods:
- Literature review based on an internal archive and cited references.
Main Results:
- Left ventricular noncompaction arises from abnormal endomyocardial embryogenesis, potentially leading to heart failure, thrombo-embolic events, and ventricular arrhythmias.
- Diagnosis is confirmed via echocardiography or MRI, revealing characteristic two-layered myocardium with prominent trabeculations, typically in the apex and inferior/lateral walls.
- The condition can be isolated or associated with other cardiac or extracardiac disorders.
Conclusions:
- Failure to identify left ventricular noncompaction can result in severe heart failure, thrombo-embolic events, ventricular tachyarrhythmias, or mortality.
- Prompt recognition of noncompaction facilitates improved patient follow-up and therapeutic strategies.
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