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[Amyotrophic lateral sclerosis. Occurrence and prognosis].

O B Tysnes1

  • 1Nevrologisk avdeling, Haukeland sykehus, Bergen.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|September 10, 1991
PubMed
Summary

This study investigated amyotrophic lateral sclerosis (ALS) epidemiology in western Norway. ALS incidence was 1.60 per 100,000, with higher prevalence in males and peak incidence in those aged 61-65.

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Area of Science:

  • Neurology
  • Epidemiology

Context:

  • Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease.
  • Understanding regional epidemiological patterns is crucial for public health planning.

Purpose:

  • To determine the incidence, prevalence, and survival rates of ALS in Hordaland county, western Norway.
  • To analyze demographic factors influencing ALS occurrence and progression.

Summary:

  • The study recorded an average annual ALS incidence of 1.60 per 100,000 population in Hordaland between 1979-1988.
  • The male to female ratio was 1:26, with peak age-adjusted incidence observed in the 61-65 age group.
  • Mean age at symptom onset was 60.9 years, with a prevalence of 3.67 per 100,000 by 1989.

Impact:

  • Findings provide essential data for understanding ALS distribution in Norway.
  • Survival analysis indicates differences based on symptom onset (bulbar vs. spinal).
  • This research contributes to the global understanding of ALS epidemiology and patient outcomes.

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