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Updated: Jun 22, 2026

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
First trimester neurosonoembryology with automated follicle tracking: preliminary findings
Lourens Pistorius1, Philip Stoutenbeek, Gerard H A Visser
1Division of Perinatology and Gynaecology, Department of Obstetrics, Wilhelmina Childrens' Hospital KE 04.123.1, University Medical Centre, PO Box 85090, Utrecht 3508 AB, The Netherlands. l.pistorius@umcutrecht.nl
Abstract:
We evaluated the feasibility of demonstration of the embryonic cerebral ventricles using three dimensional transvaginal ultrasonography and software which has been developed to automatically calculate the volume of ovarian follicles after ovarian stimulation. In four out of six subsequent ultrasound examinations which were done for determination of gestational age from eight to ten gestational weeks, sufficient resolution was obtained to demonstrate the embryonic cerebral ventricles with automated volume calculation software, yielding striking images of a dramatic stage of embryonic development.
