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Three-dimensional reconstructive analysis of intracytoplasmic lumina found in ependymomas
Nobuyuki Fukudome1, Eiji Ohno, Mamoru Mochizuki
1Department of Pathology and Clinical Cytology, Mitsubishi Chemical Medience, Itabashi-ku, Tokyo 174-0051, Japan.
Abstract:
Three-dimensional reconstructive analyses revealed that the intracytoplasmic lumina found in ependymomas were actually formed by subsidence of an extracellular membrane, resembling a volcano. This finding was compatible with cytologic and electron microscopic findings. In addition, there were many tiny thorns resembling a holly leaf on the extracellular membrane, such that cilia and microvilli on the cellular membrane discontinued cell-to-cell tight junctions.
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