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Updated: Jun 22, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
Published on: August 2, 2022
Nonenhancing brain metastases
Sasan Karimi1, Eric Lis, Saba Gilani
1Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. karimis@mskcc.org
Abstract:
The hallmark radiological finding in metastatic brain disease is multiple enhancing lesions. We report a case of metastatic lung cancer to the brain with a lack of contrast enhancement. We believe that this unusual finding is due to inadvertent "treatment" of the metastases with the antiangiogenic agent bevacizumab (Avastin).
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