Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 22, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Structural and functional changes over time in MacTel patients.

Steffen Schmitz-Valckenberg1, E E Lin Ong, Gary S Rubin

  • 1Institute of Ophthalmology, University College London, UK.

Retina (Philadelphia, Pa.)
|June 4, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Community Optometrist-Led Monitoring of Quiescent Neovascular Age-Related Macular Degeneration: The FENETRE Randomized Clinical Trial.

JAMA network open·2026
Same author

Head-to-Head Comparative Evaluation of Four Commercially Available Artificial Intelligence Systems for Detecting Referable Diabetic Retinopathy in a Tanzanian Population.

Diabetes care·2026
Same author

Determinants of vision-related quality of life in recessive Stargardt disease.

The British journal of ophthalmology·2026
Same author

Hyperreflective Foci Contiguous With the Retinal Pigment Epithelium Associated With Visual Function in Aging, Early, and Intermediate Age-Related Macular Degeneration: MACUSTAR Study Report.

American journal of ophthalmology·2026
Same author

Standardizing Measurement of Complete Retinal Pigment Epithelial and Outer Retinal Atrophy: Classification of Atrophy Meeting Report 8.

Ophthalmology. Retina·2026
Same author

Independent and openly reported head-to-head comparative validation studies of AI medical devices: a necessary step towards safe and responsible clinical AI deployment.

The Lancet. Digital health·2025

Functional and morphologic changes in Macular Telangiectasia (MacTel) over one year were minimal, likely within test-retest variability. However, reduced scotopic sensitivity indicates more severe rod dysfunction in MacTel patients.

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Visual Function

Background:

  • Idiopathic juxtafoveal retinal telangiectasia (MacTel) is a degenerative retinal disease.
  • Understanding its progression is crucial for patient management and therapeutic development.

Purpose of the Study:

  • To evaluate functional and morphologic changes in MacTel over a 1-year period.
  • To assess the significance of these changes in relation to test-retest variability.

Main Methods:

  • Nine patients with MacTel underwent repeated fine matrix mapping (FMM) and microperimetry.
  • Imaging studies were performed to assess morphologic alterations.
  • Visual acuity was measured using the Early Treatment Diabetic Retinopathy Study scale.

More Related Videos

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

Related Experiment Videos

Last Updated: Jun 22, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

Main Results:

  • Central visual acuity and microperimetry showed minimal changes, within test-retest limits.
  • Scotopic sensitivity significantly deteriorated, confirming greater rod than cone dysfunction.
  • Progression of visual field defects correlated with vascular changes and pigmented plaques.

Conclusions:

  • Observed changes in visual acuity and microperimetry are likely within test-retest variability.
  • Deterioration in scotopic sensitivity highlights rod dysfunction in MacTel.
  • Monitoring fine visual function over time may aid in evaluating interventions for MacTel.