Related Experiment Video
Updated: Jun 22, 2026

06:25
Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
Published on: March 15, 2020
Abstract:
Destruction of atrial tissue by radiofrequency ablation for preventing relapses of atrial fibrillation carries a risk of rare but frequently fatal fistula formation between the atrium and the oesophagus. Early symptoms include ischaemic disorders and gastrointestinal bleeding occurring within two weeks following the procedure.
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Esophageal Achalasia
Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
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Clinical Manifestations:
Clinical Manifestations:
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The location of esophageal perforation can vary, occurring anywhere along the esophagus.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.

