MRSA colonisation in patients admitted with hip fracture: implications for prevention of surgical site infection

David Thyagarajan1, Dakshinamurthy Sunderamoorthy, Samarthjoy Haridas

  • 1Department of Trauma & Orthopaedics, University Hospital of Wales, Cardiff & Vale NHS Trust Heath, Heath, Cardiff, United Kingdom CF14 8BH. davidskt@yahoo.co.uk

Insights

Methicillin-resistant Staphylococcus aureus (MRSA) colonization affects 5.2% of hip fracture patients. Higher MRSA rates were observed in patients from residential and nursing homes, particularly those with recent hospitalizations.

Area of Science:

  • Infectious Diseases
  • Orthopedics
  • Public Health

Background:

  • Hip fractures represent a significant orthopedic emergency.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a major healthcare-associated pathogen.
  • Understanding MRSA colonization prevalence in vulnerable patient groups is crucial for infection control.

Purpose of the Study:

  • To determine the prevalence of MRSA colonization in patients admitted with hip fractures.
  • To identify risk factors associated with MRSA colonization in this population.
  • To inform perioperative prophylaxis strategies.

Main Methods:

  • Prospective study design.
  • Inclusion of 440 sequentially admitted trauma patients with hip fractures.
  • Swab collection on admission for MRSA screening (n=403).

Main Results:

  • Overall MRSA colonization rate was 5.2% (21/403).
  • Higher colonization rates were found in patients from residential homes (10.9%) and nursing homes (17.4%) compared to those from home (3.6%).
  • 80.9% of colonized patients had a history of hospitalization within the previous year.

Conclusions:

  • MRSA colonization is prevalent in hip fracture patients, with increased risk in institutionalized individuals.
  • Recent hospitalization is a significant risk factor for MRSA carriage.
  • Perioperative prophylaxis with agents like teicoplanin should be considered for patients with a history of recent hospitalization.

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