Related Experiment Video
Updated: Jun 22, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
Isolated ovarian relapse of pre-B acute lymphoblastic leukemia: a case report
Roberto Berretta1, Angelica Barone, Martino Rolla
1Department of Obstetrics and Gynecology, University of Parma, Parma via gramsci 14 -43100, Italy. rberretz@tin.it
Background:
Acute lymphoblastic leukemia is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace normal marrow hematopoietic cells, resulting in a marked decrease in the production of normal blood cells.
Case Report:
We report a case of isolated ovarian relapse 7 years after the primary diagnosis in a patient, who was seemingly in clinical remission following unilateral ovariectomy and second-line chemotherapy.
Conclusion:
In contrast to testicular relapse, ovarian relapses in acute lymphoblastic leukemia are rarely reported. Surgical removal of the mass followed by chemotherapy is the therapeutic standard.
Related Concept Videos
Treatment Resistent Cancers
Treatment Resistant Cancers