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Updated: Jun 22, 2026
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Pairwise Growth Competition Assay for Determining the Replication Fitness of Human Immunodeficiency Viruses
Published on: May 4, 2015
Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus
Noriaki Hosoya1, Zhaohui Su, Timothy Wilkin
1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Journal of Clinical Microbiology
|June 5, 2009
Abstract:
Detection of CXCR4-using human immunodeficiency virus by the Trofile assay was compared to that by assays using virus isolates or replication-competent recombinants. Concordance with the Trofile assay was good, but assays using replicating viruses did not increase substantially the ability to detect the presence of CXCR4-using virus.
