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Updated: Jun 22, 2026
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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Human papillomavirus genotype specificity of hybrid capture 2 low-risk probe cocktail
Mario Poljak1, Bostjan J Kocjan, Anja Kovanda
1Institute of Microbiology and Immunology, University of Ljubljana, Slovenia. mario.poljak@mf.uni-lj.si
Journal of Clinical Microbiology
|June 5, 2009
Abstract:
A genotyping study of 285 Hybrid Capture 2 low-risk probe cocktail-positive specimens showed cross-reactivity with several untargeted human papillomavirus genotypes. Cross-reactivity was often clinically beneficial due to the detection of untargeted low-risk genotypes. A total of 8.4% of positive results, usually weak, were due to cross-reactivity with high-risk genotypes. Establishment of a gray zone is recommended.
