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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
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Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation

Published on: November 17, 2014

Corneal grafting and banking.

Niels Ehlers, Jesper Hjortdal, Kim Nielsen

    Developments in Ophthalmology
    |June 5, 2009
    PubMed
    Summary
    This summary is machine-generated.

    Corneal transplantation history spans centuries, evolving from early concepts to modern eye banking. Advances in preservation, like organ culture, enhance donor tissue viability and enable global exchange for better patient outcomes.

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    Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

    Published on: October 21, 2022

    Area of Science:

    • Ophthalmology
    • Transplantation Science
    • Biobanking

    Background:

    • Corneal transplantation concepts date to the late 18th century, with human grafting established over a century later.
    • Filatov's work on post-mortem corneal tissue collection was a significant advancement.
    • Eye banking history is marked by evolving tissue preservation techniques.

    Purpose of the Study:

    • To review the historical development of corneal transplantation and eye banking.
    • To highlight advancements in tissue preservation and storage methods.
    • To discuss the impact of internationalization and regulation on eye banking.

    Main Methods:

    • Historical review of corneal transplantation and eye banking milestones.
    • Analysis of the evolution of tissue preservation techniques from cold storage to organ culture.
    • Examination of the effects of international collaboration and regulatory frameworks.

    Main Results:

    • Shift from cold storage to warm storage (organ culture) improves donor cornea sterility and vitality assessment.
    • Long-term organ culture facilitates inter-center exchange and histocompatibility matching.
    • Internationalization has led to organizations like the European Eye Bank Association and increased governmental regulations.

    Conclusions:

    • Modern eye banking relies on advanced preservation techniques like organ culture for improved graft quality.
    • International collaboration and regulatory oversight are shaping the future of eye banking.
    • Future developments may focus on graft biomechanics and optics, potentially driving centralization of services.