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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: Jun 22, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Bone densitometry: current status and future perspectives.

Nicola Crabtree1, Kate Ward

  • 1Department of Nuclear Medicine, Queen Elizabeth NHS Foundation Trust Hospital, Edgbaston, Birmingham, UK. nicola.crabtree@uhb.nhs.uk

Endocrine Development
|June 5, 2009
PubMed
Summary
This summary is machine-generated.

This chapter explores bone strength and fracture risk assessment using current technologies. It reviews bone densitometry, magnetic resonance imaging, dual energy X-ray absorptiometry (DXA), and quantitative computed tomography (QCT) for pediatric bone health.

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Published on: September 28, 2017

Area of Science:

  • Orthopedics
  • Radiology
  • Pediatrics

Background:

  • Bone strength and fracture risk are critical in skeletal development.
  • Accurate quantification of bone health is essential for pediatric care.
  • Current technologies offer various methods for assessing bone properties.

Purpose of the Study:

  • To discuss determinants of bone strength and fracture risk.
  • To review current bone densitometry technologies for quantifying bone health.
  • To evaluate the application of newer technologies like MRI in pediatric skeletal assessment.

Main Methods:

  • Review of bone densitometry measurement techniques.
  • Analysis of dual energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) in children.
  • Evaluation of magnetic resonance imaging (MRI) for growing skeletons.

Main Results:

  • Bone densitometry techniques have distinct strengths and limitations, especially for pediatric scanning.
  • DXA and QCT are established tools for clinical assessment of pediatric bone health.
  • MRI presents a newer technological approach for evaluating the pediatric skeleton.

Conclusions:

  • Understanding bone strength determinants is key to managing fracture risk.
  • Appropriate selection of bone densitometry techniques is crucial for pediatric bone health assessment.
  • Emerging technologies like MRI offer complementary insights into the growing skeleton.