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Updated: Jun 22, 2026

Microfluidic Mixers for Studying Protein Folding
Published on: April 10, 2012
Design of a new static micromixer having simple structure and excellent mixing performance
Eiji Kamio1, Tsutomu Ono, Hidekazu Yoshizawa
1Department of Environmental Chemistry and Materials, Okayama University, 3-1-1, Tsushima-naka, Okayama-shi, Okayama 700-8530, Japan.
Abstract:
A novel micromixer with simple construction and excellent mixing performance is developed. The micromixer is composed of two stainless steel tubes with different diameters: one is an outer tube and another is an inner tube which fits in the outer tube. In this micromixer, one reactant fluid flows in the mixing zone from the inner tube and the other flows from the outer tube. The excellent mixing performance is confirmed by comparing the results of a Villermaux/Dushman reaction with those for the other micromixers. The developed micromixer has a mixing cascade with multiple means and an asymmetric structure to achieve effective mixing. The excellent mixing performance of the developed micromixer suggests that serial addition of multiple phenomena for mixing will give us an efficient micromixing.
