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Related Concept Videos

Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open.
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Skeletal Muscle Relaxants: Adverse Effects01:21

Skeletal Muscle Relaxants: Adverse Effects

Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
Classification of Skeletal Muscle Relaxants01:28

Classification of Skeletal Muscle Relaxants

Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...

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Related Experiment Video

Updated: Jun 22, 2026

Isokinetic Robotic Device to Improve Test-Retest and Inter-Rater Reliability for Stretch Reflex Measurements in Stroke Patients with Spasticity
08:40

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Regular stretch does not increase muscle extensibility: a randomized controlled trial.

M Ben1, L A Harvey

  • 1Rehabilitation Studies Unit, Northern Clinical School, Faculty of Medicine, University of Sydney, Sydney, Australia.

Scandinavian Journal of Medicine & Science in Sports
|June 6, 2009
PubMed
Summary

Regular stretching for six weeks did not enhance hamstring muscle extensibility in healthy individuals. However, it did improve stretch tolerance, leading to a greater range of motion without actual muscle flexibility gains.

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Area of Science:

  • Sports Medicine
  • Physiotherapy
  • Biomechanics

Background:

  • Muscle extensibility is crucial for athletic performance and injury prevention.
  • The optimal duration and frequency of stretching for improving muscle extensibility remain debated.
  • Distinguishing between actual muscle extensibility and stretch tolerance is important for effective training.

Purpose of the Study:

  • To investigate the effect of a 6-week regular stretching program on hamstring muscle extensibility.
  • To differentiate between changes in muscle extensibility and stretch tolerance following a stretching intervention.

Main Methods:

  • A randomized controlled trial involving 60 healthy participants.
  • An experimental group performed 30-minute supervised hamstring stretches 5 times/week for 6 weeks.
  • Passive hip flexion during a straight leg raise was measured using a standardized device and stretch torque.

Main Results:

  • No significant increase in passive hip flexion was observed when measured with a standardized stretch torque (mean difference: -1°, 95% CI: -3° to 2°).
  • A significant increase in passive hip flexion occurred when measured without a standardized stretch torque (mean difference: 10°, 95% CI: 6° to 14°).
  • The findings suggest improved stretch tolerance rather than increased muscle extensibility.

Conclusions:

  • Six weeks of sustained, intensive stretching does not increase hamstring muscle extensibility in healthy individuals.
  • The observed increase in range of motion is attributed to enhanced stretch tolerance, not a change in the muscle's intrinsic flexibility.
  • Clinical implications suggest focusing on stretch tolerance may be key for improving joint range of motion in specific populations.