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Updated: Jun 22, 2026

Nasal Wipes for Influenza A Virus Detection and Isolation from Swine
Published on: December 4, 2015
Origins of the new influenza A(H1N1) virus: time to take action
G M Nava1, M S Attene-Ramos, J K Ang
1College of Veterinary Medicine, National Autonomous University of Mexico, Mexico City, Mexico. gerardomnava@gmail.com
Abstract:
To gain insight into the possible origins of the 2009 outbreak of new influenza A(H1N1), we performed two independent analyses of genetic evolution of the new influenza A(H1N1) virus. Firstly, protein homology analyses of more than 400 sequences revealed that this virus most likely evolved from recent swine viruses. Secondly, phylogenetic analyses of 5,214 protein sequences of influenza A(H1N1) viruses (avian, swine and human) circulating in North America for the last two decades (from 1989 to 2009) indicated that the new influenza A(H1N1) virus possesses a distinctive evolutionary trait (genetic distinctness). This appears to be a particular characteristic in pig-human interspecies transmission of influenza A. Thus these analyses contribute to the evidence of the role of pig populations as "mixing vessels" for influenza A(H1N1) viruses.
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