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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Prognostic indicators of open globe injuries in children
Ching-Hsing Lee1, Lan Lee, Ling-Yuh Kao
1Department of Emergency Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kweishan 333, Taoyuan, Taiwan, ROC.
Insights
Pediatric open globe injuries have varied visual outcomes. Injury extent, location, and complications like endophthalmitis significantly impact prognosis in children.
Area of Science:
- Ophthalmology
- Pediatric Traumatology
- Vision Science
Background:
- Open globe injuries in children are a significant cause of vision loss.
- Identifying prognostic indicators is crucial for timely intervention and management.
Purpose of the Study:
- To identify key prognostic indicators for visual outcomes in pediatric patients with open globe injuries.
- To analyze factors influencing visual acuity following ocular trauma in children.
Main Methods:
- Retrospective chart review of 62 pediatric patients (≤16 years) treated for open globe injuries.
- Analysis of injury types, causes, and initial clinical presentations.
- Correlation of injury characteristics with final visual acuity outcomes.
Main Results:
- Sharp objects were common causes of injury.
- Visual acuity varied significantly based on injury type and extent: corneal injury only (80.8%), with lens damage (45.5%), and extensive anterior/posterior injuries (17.4%).
- Factors associated with poor visual outcomes included injury location, severity, hyphema, vitreous hemorrhage, retinal detachment, corneal wounds, and endophthalmitis.
Conclusions:
- Prognostic indicators for visual outcome in pediatric open globe injuries include injury characteristics and complications.
- Early identification of these factors can guide treatment strategies to improve visual prognosis.
- Management should focus on addressing the extent and location of injury, and preventing complications like endophthalmitis.
Purpose:
To determine the prognostic indicators of visual outcome in children with open globe injuries.
Basic Procedures:
The charts of 62 patients, 16 years of age or younger, who had been treated for open globe injuries were reviewed.
Main Findings:
The types of injury included penetrating (30 eyes), rupture (20 eyes), intraocular foreign body (10 eyes), and perforation (2 eyes). Sharp objects, such as knives or scissors, were the most common causes of open globe injuries. A visual acuity (VA) of at least 20/40 was achieved in 80.8% (21/26) of eyes with a corneal injury only, in 45.5% (5/11) of eyes with additional lens damage, and in 17.4% (4/23) of eyes with extensive anterior and posterior injuries.
Conclusions:
Unfavorable outcomes were related to the location of injury, the extent of injury, the initial presentation of hyphema, vitreous hemorrhage, retina detachment, cornea wound across the pupil, and the development of endophthalmitis.
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