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Updated: Jun 22, 2026

Using Flexible Gold-Titanium Reaction Cells to Simulate Pressure-Dependent Microbial Activity in the Context of Subsurface Biomining
Published on: October 5, 2019
Biotechnology under high pressure: applications and implications
Abram Aertsen1, Filip Meersman, Marc E G Hendrickx
1Laboratory of Food Microbiology, Leuven Food Science and Nutrition Research Center (LFoRCe), Department of Microbial and Molecular Systems (M(2)S), K.U.Leuven, Kasteelpark Arenberg 22, B-3001 Leuven, Belgium. abram.aertsen@biw.kuleuven.be
Abstract:
Pressure is a thermodynamic parameter whose unique effects on biological systems are increasingly being studied in a growing number of scientific fields. As such, the effects of high pressure are currently being investigated at different levels, ranging from proteins, enzymes and viruses to microorganisms, mammalian cells and tissues. Together with the steadily growing knowledge and understanding of high pressure effects on these increasingly complex systems, the purposeful use of high pressure has found several unique applications in bioscience over the past few years, including the disaggregation of proteins, the preparation of viral vaccines and the modulation of food functionality. In this review, recent and emerging applications of high pressure in biotechnology are presented and discussed.
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